What causes a deficiency of growth hormone?
Dr. Darwin Smith - What causes a deficiency of growth hormone? If growth hormone deficiency appears to have stopped growing, we talk about the deficit, with onset in adulthood. The most common cause of this disease is a benign pituitary tumor and its treatment. Sometimes it can happen that the tumor produces some other hormone such as Sometimes it is broken and does not produce any hormone.
Because the pituitary is stored in a small depression called the Turkish yoke, increasing tumor oppresses the surrounding healthy tissue and causes hormonal deficits. Growth hormone deficiency is usually the first to appear. Also, surgical treatment of pituitary tumor may then be the cause of reduced growth hormone secretion. Other causes of growth hormone deficiency in adults may be a tumor of the hypothalamus or the irradiation of the area.
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Some adult patients developed deficiency in childhood as a result of tumors of the hypothalamus-pituitary area or other intracranial tumors and their treatment, surgery or radiation. Often the cause is unknown (called idiopathic growth hormone deficiency). Idiopathic growth hormone deficiency detected in childhood can persist throughout life, but also may be in early adulthood has been confirmed. The reason for these discrepant findings is not entirely clear.